Alpha-glucuronidase

For beta-glucuronidase, see Beta-glucuronidase

In enzymology, an alpha-glucuronidase (Template:EC number) is an enzyme that catalyzes the chemical reaction

an alpha-D-glucuronoside + H₂O $\rightleftharpoons$ an alcohol + D-glucuronate

Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H₂O, whereas its two products are alcohol and D-glucuronate.

This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha-D-glucosiduronate glucuronohydrolase. This enzyme is also called alpha-glucosiduronase.

Structural studies

As of late 2007, 13 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

See also

• Beta-glucuronidase
• Glucuronosyl-disulfoglucosamine glucuronidase
• Glycyrrhizinate beta-glucuronidase

References

• Visser, J., Kusters van Someren, M.A., Beldman, G. and Voragen, A.G.J. (Eds.), Xylans and Xylanases, Elsevier, Amsterdam, 1992, p. 213-224.
• Template:Cite journal

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