Ureidoglycolate hydrolase
Template:Short description Template:Infobox enzyme In enzymology, an ureidoglycolate hydrolase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- (S)-ureidoglycolate + H2O glyoxylate + 2 NH3 + CO2
Thus, the two substrates of this enzyme are (S)-ureidoglycolate and H2O, whereas its 3 products are glyoxylate, NH3, and CO2.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is (S)-ureidoglycolate amidohydrolase (decarboxylating). This enzyme participates in purine metabolism.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.
References
Template:Carbon-nitrogen non-peptide hydrolases Template:Enzymes Template:Portal bar