Urea carboxylase

Template:Short description Template:Infobox enzyme In enzymology, a urea carboxylase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction

ATP + urea + HCO₃- $\rightleftharpoons$ ADP + phosphate + urea-1-carboxylate

The 3 substrates of this enzyme are ATP, urea, and HCO3-, whereas its 3 products are ADP, phosphate, and urea-1-carboxylate (allophanate).

This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is urea:carbon-dioxide ligase (ADP-forming). This enzyme participates in urea cycle and metabolism of amino groups. It employs one cofactor, biotin.

See also

• Allophanate hydrolase

References

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