UDP-sugar diphosphatase

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Template:Short description Template:Infobox enzyme In enzymology, an UDP-sugar diphosphatase (Template:EC number) is an enzyme that catalyzes the chemical reaction

UDP-sugar + H2O UMP + alpha-D-aldose 1-phosphate

Thus, the two substrates of this enzyme are UDP-sugar and H2O, whereas its two products are UMP and alpha-D-aldose 1-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is UDP-sugar sugarphosphohydrolase. Other names in common use include nucleosidediphosphate-sugar pyrophosphatase, nucleosidediphosphate-sugar diphosphatase, UDP-sugar hydrolase, and UDP-sugar pyrophosphatase.

Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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Template:Acid anhydride hydrolases Template:Enzymes Template:Portal bar


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