Tricetin 3',4',5'-O-trimethyltransferase

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Template:Short description Template:Infobox enzyme Tricetin 3',4',5'-O-trimethyltransferase (Template:EC number, FOMT, TaOMT1, TaCOMT1, TaOMT2) is an enzyme with systematic name S-adenosyl-L-methionine:tricetin 3',4',5'-O-trimethyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction

3 S-adenosyl-L-methionine + tricetin 3 S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin (overall reaction)
(1a) S-adenosyl-L-methionine + tricetin S-adenosyl-L-homocysteine + 3'-O-methyltricetin
(1b) S-adenosyl-L-methionine + 3'-O-methyltricetin S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin
(1c) S-adenosyl-L-methionine + 3',5'-O-dimethyltricetin S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin

The enzyme from Triticum aestivum catalyses the sequential O-methylation of tricetin via 3'-O-methyltricetin, 3',5'-O-methyltricetin to 3',4',5'-O-trimethyltricetin.

References

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