TRNA (guanine26-N2/guanine27-N2)-dimethyltransferase

Template:Short description Template:Infobox enzyme TRNA (guanine²⁶-N²/guanine²⁷-N²)-dimethyltransferase (Template:EC number, Trm1, tRNA (N²,N²-guanine)-dimethyltransferase, tRNA (m2(2G26) methyltransferase, Trm1[tRNA (m2(2)G26) methyltransferase]) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine²⁶-N²/guanine²⁷-N²)-dimethyltransferase. This enzyme catalyses the following chemical reaction

4 S-adenosyl-L-methionine + guanine²⁶/guanine²⁷ in tRNA $\rightleftharpoons$ 4 S-adenosyl-L-homocysteine + N²-dimethylguanine²⁶/N²-dimethylguanine²⁷ in tRNA

The enzyme from Aquifex aeolicus is similar to the TRM1 methyltransferases of archaea and eukarya.

External links

• Template:MeshName