TRNA (guanine26-N2)-dimethyltransferase

Template:Infobox enzyme TRNA (guanine²⁶-N²)-dimethyltransferase (Template:EC number, Trm1p, TRM1, tRNA (m22G26)dimethyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine²⁶-N²)-dimethyltransferase. This enzyme catalyses the following chemical reaction

2 S-adenosyl-L-methionine + guanine²⁶ in tRNA $\rightleftharpoons$ 2 S-adenosyl-L-homocysteine + N²-dimethylguanine26 in tRNA

The enzyme dissociates from its tRNA substrate between the two consecutive methylation reactions.

External links

• Template:MeshName