TRNA (guanine10-N2)-dimethyltransferase

Template:Infobox enzyme TRNA (guanine¹⁰-N²)-dimethyltransferase (Template:EC number, PAB1283, N(2),N(2)-dimethylguanosine tRNA methyltransferase, Trm-G10, PabTrm-G10, PabTrm-m2 2G10 enzyme) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine¹⁰-N²)-dimethyltransferase. This enzyme catalyses the following chemical reaction

2 S-adenosyl-L-methionine + guanine¹⁰ in tRNA $\rightleftharpoons$ 2 S-adenosyl-L-homocysteine + N²-dimethylguanine¹⁰ in tRNA (overall reaction)

(1a) S-adenosyl-L-methionine + guanine¹⁰ in tRNA $\rightleftharpoons$ S-adenosyl-L-homocysteine + N²-methylguanine¹⁰ in tRNA

(1b) S-adenosyl-L-methionine + N²-methylguanine¹⁰ in tRNA $\rightleftharpoons$ S-adenosyl-L-homocysteine + N²-dimethylguanine¹⁰ in tRNA

External links

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