TRNA (guanine-N7-)-methyltransferase
Template:Infobox enzyme Template:Lowercase title In enzymology, a tRNA (guanine-N7-)-methyltransferase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + tRNA S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine
Thus, the two substrates of this enzyme are S-adenosyl methionine and tRNA, whereas its two products are S-adenosylhomocysteine and tRNA containing N7-methylguanine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase. Other names in common use include transfer ribonucleate guanine 7-methyltransferase, 7-methylguanine transfer ribonucleate methylase, tRNA guanine 7-methyltransferase, N7-methylguanine methylase, and S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link and Template:PDB link.
References
Template:One carbon transferases Template:Enzymes Template:Portal bar