TRNA (cytosine38-C5)-methyltransferase
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Template:Short description Template:Infobox enzyme TRNA (cytosine38-C5)-methyltransferase (Template:EC number, hDNMT2 (gene), DNMT2 (gene), TRDMT1 (gene)) is an enzyme with the systematic name S-adenosyl-L-methionine:tRNA (cytosine38-C5)-methyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction:
- S-adenosyl-L-methionine + cytosine38 in tRNA S-adenosyl-L-homocysteine + 5-methylcytosine38 in tRNA
The eukaryotic enzyme catalyses methylation of cytosine38 in the anti-codon loop of tRNAAsp(GTC), tRNAVal(AAC) and tRNAGly(GCC).
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Template:One carbon transferases Template:Enzymes Template:Portal bar