TRNA (cytosine34-C5)-methyltransferase

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Template:Infobox enzyme TRNA (cytosine34-C5)-methyltransferase (Template:EC number, hTrm4 Mtase, hTrm4 methyltransferase, hTrm4 (gene), tRNA:m5C-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytosine34-C5)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytosine34 in tRNA precursor ⇌ S-adenosyl-L-homocysteine + 5-methylcytosine34 in tRNA precursor

The human enzyme is specific for C5-methylation of cytosine34 in tRNA precursors.

References

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Template:One carbon transferases Template:Enzymes Template:Portal bar

  1. ↑ Template:Cite journal
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