TRNA-dihydrouridine16/17 synthase (NAD(P)+)

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Template:Short description Template:Infobox enzyme TRNA-dihydrouridine16/17 synthase (NAD(P)+) (Template:EC number, Dus1p, tRNA-dihydrouridine synthase 1) is an enzyme with systematic name tRNA-5,6-dihydrouracil16/17:NAD(P)+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

(1) 5,6-dihydrouracil16 in tRNA + NAD(P)+ uracil16 in tRNA + NAD(P)H + H+
(2) 5,6-dihydrouracil17 in tRNA + NAD(P)+ uracil17 in tRNA + NAD(P)H + H+

This enzyme specifically modifies uracil16 and uracil17 in tRNA.

References

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