RRNA (adenine-N6-)-methyltransferase
Template:Infobox enzyme Template:Lowercase title In enzymology, a rRNA (adenine-N6-)-methyltransferase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + rRNA S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine
Thus, the two substrates of this enzyme are S-adenosyl methionine and rRNA, whereas its two products are S-adenosylhomocysteine and rRNA containing N6-methyladenine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase. Other names in common use include ribosomal ribonucleate adenine 6-methyltransferase, gene ksgA methyltransferase, ribonucleic acid-adenine (N6) methylase, ErmC 23S rRNA methyltransferase, and S-adenosyl-L-methionine:rRNA (adenine-6-N-)-methyltransferase.
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.
References
Template:One carbon transferases Template:Enzymes Template:Portal bar