Pyrrolysine—tRNAPyl ligase
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Template:Infobox enzyme Pyrrolysine—tRNAPyl ligase (Template:EnzExplorer, PylS, pyrrolysyl-tRNA synthetase) is an enzyme with systematic name L-pyrrolysine:tRNAPyl ligase (AMP-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- ATP + L-pyrrolysine + tRNAPyl AMP + diphosphate + L-pyrrolysyl-tRNAPyl
This enzyme is specific for pyrrolysine as substrate as it cannot be replaced by lysine or any of the other natural amino acids.
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Template:Ligases CO CS and CN Template:Enzymes Template:Portal bar