Pyridoxamine-phosphate transaminase

Template:Infobox enzyme In enzymology, a pyridoxamine-phosphate transaminase (Template:EC number) is an enzyme that catalyzes the chemical reaction

pyridoxamine 5'-phosphate + 2-oxoglutarate $\rightleftharpoons$ pyridoxal 5'-phosphate + D-glutamate

Thus, the two substrates of this enzyme are pyridoxamine 5'-phosphate and 2-oxoglutarate, whereas its two products are pyridoxal 5'-phosphate and D-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming). Other names in common use include pyridoxamine phosphate aminotransferase, pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase, and pyridoxamine 5'-phosphate transaminase. This enzyme participates in vitamin B₆ metabolism.

References

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