Purine imidazole-ring cyclase

Template:Infobox enzyme The enzyme purine imidazole-ring cyclase (EC 4.3.2.4) catalyzes the chemical reaction

DNA 4,6-diamino-5-formamidopyrimidine $\rightleftharpoons$ DNA adenine + H₂O

This enzyme belongs to the family of lyases, specifically amidine lyases. The systematic name of this enzyme class is DNA-4,6-diamino-5-formamidopyrimidine C⁸-N⁹-lyase (cyclizing DNA-adenine-forming). Other names in common use include DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing), DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing, DNA-adenine-forming).

References

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