Propionate—CoA ligase

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Template:Infobox enzyme In enzymology, a propionate—CoA ligase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction

ATP + propanoate + CoA AMP + diphosphate + propanoyl-CoA

The 3 substrates of this enzyme are ATP, propanoate, and CoA, whereas its 3 products are AMP, diphosphate, and propanoyl-CoA.

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is propanoate:CoA ligase (AMP-forming). This enzyme is also called propionyl-CoA synthetase. This enzyme participates in propanoate metabolism.

References

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