Pimeloyl-CoA dehydrogenase

Template:Short description Template:Infobox enzyme In enzymology, a pimeloyl-CoA dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

pimeloyl-CoA + NAD⁺ $\rightleftharpoons$ 6-carboxyhex-2-enoyl-CoA + NADH + H⁺

Thus, the two substrates of this enzyme are pimeloyl-CoA and NAD⁺, whereas its 3 products are 6-carboxyhex-2-enoyl-CoA, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is pimeloyl-CoA:NAD+ oxidoreductase. This enzyme participates in benzoate degradation via coa ligation.

References

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