Phosphopantothenoylcysteine decarboxylase

Template:Infobox enzyme The enzyme phosphopantothenoylcysteine decarboxylase (Template:EnzExplorer) catalyzes the chemical reaction

N-[(R)-4'-phosphopantothenoyl]-L-cysteine $\rightleftharpoons$ pantotheine 4'-phosphate + CO₂

This enzyme belongs to the family of lyases, to be specific the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming). This enzyme participates in coenzyme A (CoA) biosynthesis from pantothenic acid.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, and Template:PDB link.

References

• Template:Cite journal
• Template:Cite journal

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