Phosphatidate cytidylyltransferase
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Phosphatidate cytidylyltransferase (Template:EC number)[1][2][3] (also known as CDP- diacylglycerol synthase) (CDS) is the enzyme that catalyzes the synthesis of CDP-diacylglycerol from cytidine triphosphate and phosphatidate.
- CTP + phosphatidate diphosphate + CDP-diacylglycerol
Thus, the two substrates of this enzyme are cytidine triphosphate, or CTP, and phosphatidate, whereas its two products are diphosphate and CDP-diacylglycerol.
CDP-diacylglycerol is an important branch point intermediate in both prokaryotic and eukaryotic organisms. CDS is a membrane-bound enzyme.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is Template:Chem name. Other names in common use include Template:Chem name, Template:Chem name, Template:Chem name, Template:Chem name, Template:Chem name, Template:Chem name, Template:Chem name, Template:Chem name, Template:Chem name, and CDP-DG. This enzyme participates in glycerophospholipid metabolism and phosphatidylinositol signaling system.