Non-specific polyamine oxidase

Template:Short description Template:Infobox enzyme Non-specific polyamine oxidase (Template:EC number, polyamine oxidase, Fms1, AtPAO3) is an enzyme with systematic name polyamine:oxygen oxidoreductase (3-aminopropanal or 3-acetamidopropanal-forming).^[1]^[2]^[3] This enzyme catalyses the following chemical reaction

(1) spermine + O₂ + H₂O

⇌

(2) spermidine + O₂ + H₂O

⇌

putrescine + 3-aminopropanal + H₂O₂

(3) N¹-acetylspermine + O₂ + H₂O

⇌

spermidine + 3-acetamidopropanal + H₂O₂

(4) N¹-acetylspermidine + O₂ + H₂O

⇌

putrescine + 3-acetamidopropanal + H₂O₂

This enzyme is flavoprotein (FAD).

References