N-formylmethionylaminoacyl-tRNA deformylase
Template:Infobox enzyme In enzymology, a N-formylmethionylaminoacyl-tRNA deformylase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- N-formyl-L-methionylaminoacyl-tRNA + H2O formate + L-methionylaminoacyl-tRNA
Thus, the two substrates of this enzyme are N-formyl-L-methionylaminoacyl-tRNA and H2O, whereas its two products are formate and L-methionylaminoacyl-tRNA.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-formyl-L-methionylaminoacyl-tRNA amidohydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, and Template:PDB link.
References
Template:Carbon-nitrogen non-peptide hydrolases Template:Enzymes Template:Portal bar