N-acyl-D-amino-acid deacylase

Template:Infobox enzyme In enzymology, a N-acyl-D-amino-acid deacylase (Template:EC number) is an enzyme that catalyzes the chemical reaction

N-acyl-D-amino acid + H₂O $\rightleftharpoons$ an acid + D-amino acid

Thus, the two substrates of this enzyme are N-acyl-D-amino acid and H₂O, whereas its two products are acid and D-amino acid.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-acyl-D-amino acid amidohydrolase. It employs one cofactor, zinc.

Structural studies

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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