Mannose-1-phosphate guanylyltransferase (GDP)

Template:Infobox enzyme In enzymology, a mannose-1-phosphate guanylyltransferase (GDP) (Template:EC number) is an enzyme that catalyzes the chemical reaction

GDP + alpha-D-mannose 1-phosphate $\rightleftharpoons$ phosphate + GDP-mannose

Thus, the two substrates of this enzyme are GDP and alpha-D-mannose 1-phosphate, whereas its two products are phosphate and GDP-mannose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GDP:alpha-D-mannose-1-phosphate guanylyltransferase. This enzyme participates in fructose and mannose metabolism.

Other common names

• GDP mannose phosphorylase
• Mannose 1-phosphate (guanosine diphosphate) guanylyltransferase
• GDP mannose phosphorylase
• GDP-mannose 1-phosphate guanylyltransferase
• Guanosine diphosphate-mannose 1-phosphate guanylyltransferase
• Guanosine diphosphomannose phosphorylase
• Mannose 1-phosphate guanylyltransferase
• GDP:D-mannose-1-phosphate guanylyltransferase

References

• Template:Cite journal

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