Malate—CoA ligase
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Template:Infobox enzyme In enzymology, a malate—CoA ligase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction
- ATP + malate + CoA ADP + phosphate + malyl-CoA
The 3 substrates of this enzyme are ATP, malate, and CoA, whereas its 3 products are ADP, phosphate, and malyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is malate:CoA ligase (ADP-forming). Other names in common use include malyl-CoA synthetase, malyl coenzyme A synthetase, and malate thiokinase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
References
Template:Ligases CO CS and CN Template:Enzymes Template:Portal bar