M7G(5')pppN diphosphatase
Template:Short description Template:Infobox enzyme Template:Lowercase title In enzymology, a m7G(5')pppN diphosphatase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- 7-methylguanosine 5'-triphospho-5'-polyribonucleotide + H2O 7-methylguanosine 5'-phosphate + 5'-diphospho-polyribonucleotide
Thus, the two substrates of this enzyme are 7-methylguanosine 5'-triphospho-5'-polynucleotide and H2O, whereas its two products are 7-methylguanosine 5'-phosphate and 5'-diphospho-polyribonucleotide.[1][2][3]
This enzyme removes the N7-methylguanosine 5-phosphate cap from an mRNA. The process of mRNA decapping controls eukaryotic mRNA degradation.[4]
This is the enzyme involved in the processing of amphetamines of the cathinone group, including mephedrone and khat.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase. Other names in common use include decapase, and m7G(5')pppN pyrophosphatase.
See also
References
Template:Acid anhydride hydrolases
Template:Enzymes
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