Long-chain acyl-CoA dehydrogenase
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Template:Infobox enzyme Long-chain acyl-CoA dehydrogenase (Template:EC number, palmitoyl-CoA dehydrogenase, palmitoyl-coenzyme A dehydrogenase, long-chain acyl-coenzyme A dehydrogenase, long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase, ACADL (gene).) is an enzyme with systematic name long-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- a long-chain acyl-CoA + electron-transfer flavoprotein a long-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein
This enzyme contains FAD as prosthetic group and participates in fatty acid metabolism and PPAR signaling pathway.[6] Mitochondrial mutations in this enzyme may be associated with some forms of dilated cardiomyopathy.
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Template:CH-CH oxidoreductases Template:Enzymes Template:Portal bar