Lactate—malate transhydrogenase
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Template:Infobox enzyme In enzymology, a lactate—malate transhydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- (S)-lactate + oxaloacetate pyruvate + malate
Thus, the two substrates of this enzyme are (S)-lactate and oxaloacetate, whereas its two products are pyruvate and malate.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (S)-lactate:oxaloacetate oxidoreductase. This enzyme is also called malate-lactate transhydrogenase. This enzyme participates in pyruvate metabolism. It employs one cofactor, nicotinamide D-ribonucleotide.
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Further reading
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