L-aminoadipate-semialdehyde dehydrogenase

Template:Infobox enzyme In enzymology, a L-aminoadipate-semialdehyde dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

L-2-aminoadipate 6-semialdehyde + NAD(P)+ + H₂O $\rightleftharpoons$ L-2-aminoadipate + NAD(P)H + H⁺

The 4 substrates of this enzyme are L-2-aminoadipate 6-semialdehyde, NAD⁺, NADP⁺, and H₂O, whereas its 4 products are L-2-aminoadipate, NADH, NADPH, and H⁺.

This enzyme participates in lysine biosynthesis and biodegradation.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase. Other names in common use include:

• aminoadipate semialdehyde dehydrogenase,
• 2-aminoadipate semialdehyde dehydrogenase,
• alpha-aminoadipate-semialdehyde dehydrogenase,
• alpha-aminoadipate reductase,
• 2-aminoadipic semialdehyde dehydrogenase,
• L-alpha-aminoadipate delta-semialdehyde oxidoreductase,
• L-alpha-aminoadipate delta-semialdehyde:NAD+ oxidoreductase,
• L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine,
• and dinucleotide oxidoreductase.

References

• Template:Cite journal

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