Isocitrate dehydrogenase (NADP+) kinase

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Template:Infobox enzyme In enzymology, a [isocitrate dehydrogenase (NADP+)] kinase (Template:EC number) is an enzyme that catalyzes the chemical reaction:

ATP + [isocitrate dehydrogenase (NADP+)] ADP + [isocitrate dehydrogenase (NADP+)] phosphate

Thus, the two substrates of this enzyme are ATP and isocitrate dehydrogenase (NADP+), whereas its two products are ADP and isocitrate dehydrogenase (NADP+) phosphate.

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases).

Other names

The systematic name of this enzyme class is ATP:[isocitrate dehydrogenase (NADP+)] phosphotransferase. Other names in common use include [isocitrate dehydrogenase (NADP+)] kinase, ICDH kinase/phosphatase, IDH kinase, IDH kinase/phosphatase, IDH-K/P, IDHK/P, isocitrate dehydrogenase kinase (phosphorylating), isocitrate dehydrogenase kinase/phosphatase, and STK3.

References

Template:Serine/threonine-specific protein kinases Template:Enzymes Template:Portal bar


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