Inositol-polyphosphate 5-phosphatase
Template:Short description Template:Infobox enzyme The enzyme inositol-polyphosphate 5-phosphatase (Template:EC number), systematic name 1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase, catalyses the following reactions:
- (1) D-myo-inositol 1,4,5-trisphosphate + H2O myo-inositol 1,4-bisphosphate + phosphate
- (2) 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O 1D-myo-inositol 1,3,4-trisphosphate + phosphate
Ten mammalian isoforms are known.[1]
Other names of this enzyme include type I inositol-polyphosphate phosphatase, inositol trisphosphate phosphomonoesterase, InsP3/Ins(1,3,4,5)P4 5-phosphatase, inosine triphosphatase, D-myo-inositol 1,4,5-triphosphate 5-phosphatase, D-myo-inositol 1,4,5-trisphosphate 5-phosphatase, L-myo-inositol 1,4,5-trisphosphate-monoesterase, inositol phosphate 5-phosphomonoesterase, inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase, Ins(1,4,5)P3 5-phosphataseD-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase, inositol 1,4,5-trisphosphate phosphatase, inositol polyphosphate-5-phosphatase, myo-inositol-1,4,5-trisphosphate 5-phosphatase, inositol-1,4,5-trisphosphate 5-phosphatase.[2][3][4][5]