Hydroxypyruvate reductase

Template:Infobox enzyme In enzymology, a hydroxypyruvate reductase (Template:EC number) is an enzyme that catalyzes the chemical reaction

D-glycerate + NAD(P)+ $\rightleftharpoons$ hydroxypyruvate + NAD(P)H + H⁺

The 3 substrates of this enzyme are D-glycerate, NAD⁺, and NADP⁺, whereas its 4 products are hydroxypyruvate, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is D-glycerate:NADP⁺ 2-oxidoreductase. Other names in common use include beta-hydroxypyruvate reductase, NADH:hydroxypyruvate reductase, and D-glycerate dehydrogenase. This enzyme participates in glycine, serine and threonine metabolism and glyoxylate and dicarboxylate metabolism.

See also

• Oxidoreductases
• Enzymes
• Enzyme Commission number (EC number)

References

• Template:Cite journal
• Template:Cite journal
• Template:Cite journal

Template:1.1.1-enzyme-stub