Hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)

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Template:Short description Template:Infobox enzyme Hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) (Template:EC number, HexPS, hexaprenyl pyrophosphate synthetase, hexaprenyl diphosphate synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 3 isopentenyl units).[1][2][3] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate 3 diphosphate + all-trans-hexaprenyl diphosphate

The enzyme prefers farnesyl diphosphate to geranylgeranyl diphosphate as an allylic substrate.

References

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