Guanosine-5'-triphosphate,3'-diphosphate diphosphatase
Template:Short description Template:Infobox enzyme In enzymology, a guanosine-5'-triphosphate,3'-diphosphate diphosphatase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- guanosine 5'-triphosphate,3'-diphosphate + H2O guanosine 5'-diphosphate,3'-diphosphate + phosphate
Thus, the two substrates of this enzyme are guanosine 5'-triphosphate,3'-diphosphate and H2O, whereas its two products are guanosine 5'-diphosphate,3'-diphosphate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase. Other names in common use include pppGpp 5'-phosphohydrolase, guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase, guanosine pentaphosphatase, guanosine pentaphosphate phosphatase, guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase, and guanosine pentaphosphate phosphohydrolase. This enzyme participates in purine metabolism.
Structural studies
As of late 2007Template:Update inline, two structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link and Template:PDB link.
References
Template:Acid anhydride hydrolases Template:Enzymes Template:Portal bar