Glycine/sarcosine N-methyltransferase

Template:Infobox enzyme Glycine/sarcosine N-methyltransferase (Template:EC number, ApGSMT, glycine-sarcosine methyltransferase, GSMT, GMT, glycine sarcosine N-methyltransferase, S-adenosyl-L-methionine:sarcosine N-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:glycine(or sarcosine) N-methyltransferase (sarcosine(or N,N-dimethylglycine)-forming). This enzyme catalyses the following chemical reaction

2 S-adenosyl-L-methionine + glycine $\rightleftharpoons$ 2 S-adenosyl-L-homocysteine + N,N-dimethylglycine (overall reaction)

(1a) S-adenosyl-L-methionine + glycine $\rightleftharpoons$ S-adenosyl-L-homocysteine + sarcosine

(1b) S-adenosyl-L-methionine + sarcosine $\rightleftharpoons$ S-adenosyl-L-homocysteine + N,N-dimethylglycine

This enzyme participates in biosynthesis of betaine from glycine in cyanobacterium Aphanocthece halophytica.

External links

• Template:MeshName