Glutarate-semialdehyde dehydrogenase

Template:Infobox enzyme In enzymology, a glutarate-semialdehyde dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

glutarate semialdehyde + NAD⁺ + H₂O $\rightleftharpoons$ glutarate + NADH + 2 H⁺

The 3 substrates of this enzyme are glutarate semialdehyde, NAD⁺, and H₂O, whereas its 3 products are glutarate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glutarate-semialdehyde:NAD+ oxidoreductase. This enzyme is also called glutarate semialdehyde dehydrogenase. This enzyme participates in lysine degradation.

References

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