Glutamine—pyruvate transaminase
Template:Infobox enzyme In enzymology, a glutamine-pyruvate transaminase (Template:EC number) is an enzyme that catalyzes the chemical reaction
- L-glutamine + pyruvate 2-oxoglutaramate + L-alanine
Thus, the two substrates of this enzyme are L-glutamine and pyruvate, whereas its two products are 2-oxoglutaramate and L-alanine.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-glutamine:pyruvate aminotransferase. Other names in common use include glutaminase II, L-glutamine transaminase L, and glutamine-oxo-acid transaminase. This enzyme participates in glutamate metabolism. It employs one cofactor, pyridoxal phosphate.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, and Template:PDB link.
References
Template:Nitrogenous transferases Template:Enzymes Template:Portal bar