Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-b-N-acetylgalactosaminyltransferase

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Template:Short description Template:Infobox enzyme Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase (Template:EC number, N-acetylgalactosaminyltransferase II, UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase, chondroitin synthase, glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II) is an enzyme with systematic name UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase.[1][2][3][4] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-D-galactosamine + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan ⇌ UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan

This enzyme is involved in the biosynthesis of chondroitin sulfate.

References

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Template:Glycosyltransferases Template:Enzymes Template:Portal bar

  1. ↑ Template:Cite journal
  2. ↑ Template:Cite journal
  3. ↑ Template:Cite journal
  4. ↑ Template:Cite journal
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