Glucosamine-1-phosphate N-acetyltransferase

Template:Infobox enzyme In enzymology, a glucosamine-1-phosphate N-acetyltransferase (Template:EC number) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + alpha-D-glucosamine 1-phosphate $\rightleftharpoons$ CoA + N-acetyl-alpha-D-glucosamine 1-phosphate

Thus, the two substrates of this enzyme are acetyl-CoA and alpha-D-glucosamine 1-phosphate, whereas its two products are CoA and N-acetyl-alpha-D-glucosamine 1-phosphate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:alpha-D-glucosamine-1-phosphate N-acetyltransferase. This enzyme participates in aminosugars metabolism.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, and Template:PDB link.

References

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