Dolichyl-phosphate beta-D-mannosyltransferase

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Template:Short description Template:Infobox enzyme In enzymology, a dolichyl-phosphate beta-D-mannosyltransferase (Template:EC number) is an enzyme that catalyzes the chemical reaction

GDP-mannose + dolichyl phosphate GDP + dolichyl D-mannosyl phosphate

Thus, the two substrates of this enzyme are GDP-mannose and dolichyl phosphate, whereas its two products are GDP and dolichyl D-mannosyl phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase. Other names in common use include GDP-Man:DolP mannosyltransferase, dolichyl mannosyl phosphate synthase, dolichyl-phospho-mannose synthase, GDP-mannose:dolichyl-phosphate mannosyltransferase, guanosine diphosphomannose-dolichol phosphate mannosyltransferase, dolichol phosphate mannose synthase, dolichyl phosphate mannosyltransferase, dolichyl-phosphate mannose synthase, GDP-mannose-dolichol phosphate mannosyltransferase, GDP-mannose-dolichylmonophosphate mannosyltransferase, mannosylphosphodolichol synthase, and mannosylphosphoryldolichol synthase. This enzyme participates in n-glycan biosynthesis.

References

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