Diacylglycerol cholinephosphotransferase

Template:Short description Template:Infobox enzyme In enzymology, a diacylglycerol cholinephosphotransferase (Template:EC number) is an enzyme that catalyzes the chemical reaction

CDP-choline + 1,2-diacylglycerol $\rightleftharpoons$ CMP + a phosphatidylcholine

Thus, the two substrates of this enzyme are CDP-choline and 1,2-diacylglycerol, whereas its two products are CMP and phosphatidylcholine.

Classification

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups.

Nomenclature

The systematic name of this enzyme class is CDP choline:1,2-diacylglycerol cholinephosphotransferase. Other names in common use include: Template:Div col

• 1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase,
• 1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase,
• 1-alkyl-2-acetylglycerol cholinephosphotransferase,
• alkylacylglycerol choline phosphotransferase,
• alkylacylglycerol cholinephosphotransferase,
• CDP-choline diglyceride phosphotransferase,
• cholinephosphotransferase,
• CPT,
• cytidine diphosphocholine glyceride transferase,
• cytidine diphosphorylcholine diglyceride transferase,
• diacylglycerol choline phosphotransferase,
• phosphocholine diacylglyceroltransferase,
• phosphorylcholine-glyceride transferase, and
• sn-1,2-diacylglycerol cholinephosphotransferase.

Biological role

This enzyme participates in 3 metabolic pathways: aminophosphonate metabolism, glycerophospholipid metabolism, and ether lipid metabolism.

References

• Template:Cite journal
• Template:Cite journal
• Template:Cite journal

Template:2.7-enzyme-stub