Deoxyuridine phosphorylase
Template:Short description Template:Infobox enzyme In enzymology, a deoxyuridine phosphorylase is an enzyme that catalyzes the chemical reaction
- 2'-deoxyuridine + phosphate uracil + 2-deoxy-alpha-D-ribose 1-phosphate
Thus, the two substrates of this enzyme are 2'-deoxyuridine and phosphate, whereas its two products are uracil and 2-deoxy-alpha-D-ribose 1-phosphate.
No enzyme is known to be specific for this reaction, hence the EC number originally assigned to this enzyme function (EC 2.4.2.23) was deleted by the IUBMB in 2013.[1] The reaction is catalysed by Template:EC number, pyrimidine-nucleoside phosphorylase, Template:EC number, uridine phosphorylase, and Template:EC number, thymidine phosphorylase.
These enzymes belong to the family of glycosyltransferases, specifically the pentosyltransferases. They participate in pyrimidine metabolism.
References
Template:Glycosyltransferases Template:Enzymes Template:Portal bar