DCTP deaminase (dUMP-forming)
Template:Infobox enzyme Template:Lowercase title In enzymology, a dCTP deaminase (dUMP-forming) (Template:EC number) is an enzyme that catalyzes the chemical reaction
- dCTP + 2 H2O dUMP + diphosphate + NH3
Thus, the two substrates of this enzyme are dCTP and H2O, whereas its 3 products are dUMP, diphosphate, and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is dCTP aminohydrolase (dUMP-forming). This enzyme participates in pyrimidine metabolism.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, and Template:PDB link.
References
Template:Carbon-nitrogen non-peptide hydrolases Template:Enzymes Template:Portal bar