D-alanine—(R)-lactate ligase

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Template:Infobox enzyme D-alanine—(R)-lactate ligase (Template:EnzExplorer, VanA, VanB, VanD) is an enzyme with systematic name D-alanine:(R)-lactate ligase (ADP-forming).[1][2][3] This enzyme catalyses the following chemical reaction

D-alanine + (R)-lactate + ATP D-alanyl-(R)-lactate + ADP + phosphate

The product of this enzyme can be incorporated into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-alanine dipeptide.

References

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