Cytochrome-c3 hydrogenase

Template:Short description Template:Infobox enzyme In enzymology, a cytochrome-c3 hydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

2 H₂ + ferricytochrome c₃ $\rightleftharpoons$ 4 H⁺ + ferrocytochrome c₃

Thus, the two substrates of this enzyme are H₂ and ferricytochrome c3, whereas its two products are H⁺ and ferrocytochrome c3.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with a cytochrome as acceptor. The systematic name of this enzyme class is hydrogen:ferricytochrome-c3 oxidoreductase. Other names in common use include H2:ferricytochrome c3 oxidoreductase, cytochrome c3 reductase, cytochrome hydrogenase, and hydrogenase [ambiguous]. It has 3 cofactors: iron, Nickel, and Iron-sulfur.

Structural studies

As of late 2007, 19 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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