Cis-2-enoyl-CoA reductase (NADPH)

Template:Short description Template:Infobox enzyme In enzymology, a cis-2-enoyl-CoA reductase (NADPH) (Template:EC number) is an enzyme that catalyzes the chemical reaction

acyl-CoA + NADP⁺ $\rightleftharpoons$ cis-2,3-dehydroacyl-CoA + NADPH + H⁺

Thus, the two substrates of this enzyme are acyl-CoA and NADP⁺, whereas its 3 products are cis-2,3-dehydroacyl-CoA, NADPH, and H⁺.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is acyl-CoA:NADP+ cis-2-oxidoreductase. Other names in common use include NADPH-dependent cis-enoyl-CoA reductase, reductase, cis-2-enoyl coenzyme A, cis-2-enoyl-coenzyme A reductase, and cis-2-enoyl-CoA reductase (NADPH).

Further reading

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