Cinnamyl-alcohol dehydrogenase

Template:Short description Template:Infobox enzyme In enzymology, a cinnamyl-alcohol dehydrogenase (Template:EC number) is an enzyme that catalyzes the chemical reaction

cinnamyl alcohol + NADP⁺ $\rightleftharpoons$ cinnamaldehyde + NADPH + H⁺

Thus, the two substrates of this enzyme are cinnamyl alcohol and NADP⁺, whereas its 3 products are cinnamaldehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is cinnamyl-alcohol:NADP⁺ oxidoreductase. Other names in common use include cinnamyl alcohol dehydrogenase, and CAD. This enzyme participates in phenylpropanoid biosynthesis.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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