Chlordecone reductase

Template:Short description Template:Infobox enzyme In enzymology, a chlordecone reductase (Template:EC number) is an enzyme that catalyzes the chemical reaction

chlordecone alcohol + NADP⁺ $\rightleftharpoons$ chlordecone + NADPH + H⁺

Thus, the two substrates of this enzyme are chlordecone alcohol and NADP⁺, whereas its 3 products are chlordecone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is chlordecone-alcohol:NADP⁺ 2-oxidoreductase. This enzyme is also called CDR.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Template:PDB link.

References

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