Carbamate kinase

Template:Short description Template:Infobox enzyme In enzymology, a carbamate kinase (Template:EC number) is an enzyme that catalyzes the chemical reaction

ATP + NH₃ + CO₂ $\rightleftharpoons$ ADP + carbamoyl phosphate

The 3 substrates of this enzyme are ATP, NH₃, and CO₂, whereas its two products are ADP and carbamoyl phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:carbamate phosphotransferase. Other names in common use include CKase, carbamoyl phosphokinase, and carbamyl phosphokinase. This enzyme participates in 4 metabolic pathways: purine metabolism, glutamate metabolism, arginine and proline metabolism, and nitrogen metabolism.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, and Template:PDB link.

References

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