Aspartate 1-decarboxylase

Template:Infobox enzyme The enzyme aspartate 1-decarboxylase (Template:EnzExplorer) catalyzes the chemical reaction

L-aspartate $\rightleftharpoons$ beta-alanine + CO₂

Hence, this enzyme has one substrate, L-aspartate, and two products, beta-alanine and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-aspartate 1-carboxy-lyase (beta-alanine-forming). Other names in common use include aspartate alpha-decarboxylase, L-aspartate alpha-decarboxylase, aspartic alpha-decarboxylase, and L-aspartate 1-carboxy-lyase. This enzyme participates in alanine and aspartate metabolism and beta-alanine metabolism.

Structural studies

Template:As of, 12 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

• Template:Cite journal

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